The other day After Effects crashed on me during a save. I'd already saved recently so it wasn't such a big problem. I reopened the project and resumed working where I left off. I made a few changes and pressed Cmd-S to save, and After Effects crashed again, in exactly the same manner. This looked like a recurring problem, and I managed to replicate the crash a few times.
Now CS3 is not new software, it's four years old. However I found an update online, taking my freshly-installed version 8.0.0 to the updated version 8.0.2. Unfortunately this did not fix the crashing problem.